To investigate the plasma kinetics of quercetin derived from hard capsules filled with onion skin extract powder or quercetin dihydrate in humans. Higher plasma quercetin levels following oral administration of an onion skin extract compared with pure quercetin dihydrate in humans.īurak, Constanze Brüll, Verena Langguth, Peter Zimmermann, Benno F Stoffel-Wagner, Birgit Sausen, Udo Stehle, Peter Wolffram, Siegfried Egert, Sarah
Detailed LC-MS analysis reveals the presence of more methylated oligomers compared to acetylated forms in the digests. is obtained with 5.2IU/mL at a time scale of 15-30min. In contrast, maximum DP4 production of 5.2-5.5% (w/w) d.m. At these conditions the production amounts 2.5-3.0% (w/w) d.m for DP2 and 5.5-5.6% (w/w) d.m for DP3 respectively. The experiments reveal that the highest amount of DP2 and DP3 is obtained at a time scale of 75-90min with an EPG-M2 concentration of 26IU/mL. Treatment of the extracted crude onion skin's pectin with various enzymes (EPG-M2, Viscozyme and Pectinase) shows that EPG-M2 is the most appropriate enzyme for tailored POS production. The process is based on a two-stage process consisting of a chelator-based crude pectin extraction followed by a controlled enzymatic hydrolysis. Onion skins are evaluated as a new raw material for the enzymatic production of pectic oligosaccharides (POS) with a targeted degree of polymerization (DP). Įnzymatic production of pectic oligosaccharides from onion skins.īabbar, Neha Baldassarre, Stefania Maesen, Miranda Prandi, Barbara Dejonghe, Winnie Sforza, Stefano Elst, Kathy It is critical to prevent onions infected by sour skin from entering storage rooms or. It not only causes substantial economic loss from diseased onions but also could lead to pulmonary infection in humans. Sour skin is a major onion disease caused by the bacterium Burkholderia cepacia (B. USDA-ARS?s Scientific Manuscript database Near-infrared Hyperspectral Reflectance Imaging for Early Detection of Sour Skin Disease in Vidalia Sweet Onions It was concluded that the outer skin of these foods are not suitable as a long-term postirradiation monitor. The ESR signal intensity increased with absorbed dose, however, the radiation-induced signal decayed slowly with time. In all spectra only a single resonance (g = 2.00) was observed. The ESR spectra of the dry, outer skin of onion, red onion, garlic, and shallot were measured before and after irradiation. The present findings suggest that onion's major active compound, quercetin, may be a potential adjuvant for treating uterine disorders.Desrosiers, Marc F.
The results indicated that (1) for contractions induced by PGF 2α-, oxytocin-, and carbachol, quercetin showed the most potent suppressing effect among the tested flavonoids (2) Ca 2+-dependent uterine contractions were inhibited by quercetin (3) quercetin reduced the PGF 2α-elicited Ca 2+ responses in human uterine smooth muscle cells (4) quercetin inhibited uterine contractions stimulated by Ca 2+ channel activator and depolarisation in response to high K + (5) quercetin was able to block Ca 2+ influx through voltage-operated Ca 2+ channels in plasma membrane and (6) quercetin effectively reduced PGF 2α-induced contractions through the administration of increasing doses of 10, 25, and 50 mg/kg in rats.
In vitro and in vivo contractile activities of the uteri were determined using uterine horns isolated from adult rats. This study aimed to investigate the modulatory effects of quercetin that is a main flavonoid in onion on uterine contractility and its possible underlying mechanisms. Dysmenorrhoea is considered to be caused by excessive levels of prostaglandins, which stimulate abnormal uterine contractions.